Bloody Palace available in DMC5

Bloody Palace has been a part of the series since DMC2. It's basically a 101 floor dungeon that will test you and push your skills to the limits.

To unlock this new mode you'll have to beat the game on Human or Devil Hunter mode and after the end credits, you will find the new mode in the main menu. As you reach higher floors the foes and bosses will get tougher and the characters will face different enemies they haven't fought in the main game (Dante can fight against Goliath or Nero against Cavaliere Angelo).

There's also some interesting info about some upcoming content but there's no confirmation as of yet:

Datamines have suggested other features are down the line for Devil May Cry 5, such as new characters, but there's been no confirmation from Capcom as of yet.